Decreased expression of miR-29 family associated with autoimmune myasthenia gravis

Decreased expression of miR-29 family associated with autoimmune myasthenia gravis

Abstract Background Myasthenia gravis (MG) is a rare autoimmune disease mainly mediated by autoantibodies against the acetylcholine receptor (AChR) at the neuromuscular junction. The thymus is the effector organ, and its removal alleviates the symptoms of the disease. In the early-onset form of MG,...

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Bibliographic Details
Main Authors: Mélanie A. Cron, Cloé A. Payet, Odessa-Maud Fayet, Solène Maillard, Frédérique Truffault, Elie Fadel, Julien Guihaire, Sonia Berrih-Aknin, Adrian Liston, Rozen Le Panse
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Journal of Neuroinflammation
Subjects:
microRNAs
DICER
Thymus
Thymic epithelial cells
Experimental autoimmune myasthenia gravis
Interferon-β
Online Access:http://link.springer.com/article/10.1186/s12974-020-01958-3

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http://link.springer.com/article/10.1186/s12974-020-01958-3

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