Targeted Delivery of Nanoparticulate Cytochrome C into Glioma Cells Through the Proton-Coupled Folate Transporter

Targeted Delivery of Nanoparticulate Cytochrome C into Glioma Cells Through the Proton-Coupled Folate Transporter

In this study, we identified the proton-coupled folate transporter (PCFT) as a route for targeted delivery of drugs to some gliomas. Using the techniques of confocal imaging, quantitative reverse transcription-polymerase chain reaction (qRT-PCR), and small interfering (siRNA) knockdown against the P...

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Bibliographic Details
Main Authors: Yuriy V. Kucheryavykh, Josue Davila, Jescelica Ortiz-Rivera, Mikhael Inyushin, Luis Almodovar, Miguel Mayol, Moraima Morales-Cruz, Alejandra Cruz-Montañez, Vanessa Barcelo-Bovea, Kai Griebenow, Lilia Y. Kucheryavykh
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Biomolecules
Subjects:
glioma
proton-coupled folate transporter
folate receptor 1
Online Access:https://www.mdpi.com/2218-273X/9/4/154

Internet

https://www.mdpi.com/2218-273X/9/4/154

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