Regulation of p14<sup>ARF </sup>expression by miR-24: a potential mechanism compromising the p53 response during retinoblastoma development
<p>Abstract</p> <p>Background</p> <p>Most human cancers show inactivation of both pRB- and p53-pathways. While retinoblastomas are initiated by loss of the <it>RB1 </it>tumor suppressor gene, <it>TP53 </it>mutations have not been found. High expr...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-02-01
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Series: | BMC Cancer |
Online Access: | http://www.biomedcentral.com/1471-2407/12/69 |