A key role for E-cadherin in intestinal homeostasis and Paneth cell maturation.

<h4>Background</h4>E-cadherin is a major component of adherens junctions. Impaired expression of E-cadherin in the small intestine and colon has been linked to a disturbed intestinal homeostasis and barrier function. Down-regulation of E-cadherin is associated with the pathogenesis of in...

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Main Authors: Marlon R Schneider, Maik Dahlhoff, David Horst, Benjamin Hirschi, Konrad Trülzsch, Josef Müller-Höcker, Roger Vogelmann, Michael Allgäuer, Markus Gerhard, Sylvia Steininger, Eckhard Wolf, Frank T Kolligs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21179475/?tool=EBI