Heterologous influenza vRNA segments with identical non-coding sequences stimulate viral RNA replication in <it>trans</it>

<p>Abstract</p> <p>The initiation of transcription and replication of influenza A virus requires the 5' and 3' ends of vRNA. Here, the role of segment-specific non-coding sequences of influenza A virus on viral RNA synthesis was studied. Recombinant viruses, with the nons...

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Bibliographic Details
Main Authors: Malik Peiris J S, Cheung Timothy KW, Li Olive TW, Ng Stella SF, Poon Leo LM
Format: Article
Language:English
Published: BMC 2008-01-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/5/1/2