DASC, a sensitive classifier for measuring discrete early stages in clathrin-mediated endocytosis

DASC, a sensitive classifier for measuring discrete early stages in clathrin-mediated endocytosis

Clathrin-mediated endocytosis (CME) in mammalian cells is driven by resilient machinery that includes >70 endocytic accessory proteins (EAP). Accordingly, perturbation of individual EAPs often results in minor effects on biochemical measurements of CME, thus providing inconclusive/misleading...

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Bibliographic Details
Main Authors: Xinxin Wang, Zhiming Chen, Marcel Mettlen, Jungsik Noh, Sandra L Schmid, Gaudenz Danuser
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-04-01
Series:eLife
Subjects:
endocytosis
unbiased classification
endocytic accessory proteins
Online Access:https://elifesciences.org/articles/53686

Internet

https://elifesciences.org/articles/53686

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