Modulation of Ras/ERK and Phosphoinositide Signaling by Long-Chain n-3 PUFA in Breast Cancer and Their Potential Complementary Role in Combination with Targeted Drugs

Modulation of Ras/ERK and Phosphoinositide Signaling by Long-Chain n-3 PUFA in Breast Cancer and Their Potential Complementary Role in Combination with Targeted Drugs

A potential complementary role of the dietary long-chain n-3 polyunsaturated fatty acids (LCn-3 PUFA) in combination with innovative mono-targeted therapies has recently been proposed. These compounds are thought to act pleiotropically to prevent the development and progression of a variety of cance...

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Bibliographic Details
Main Authors: Simona Serini, Gabriella Calviello
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Nutrients
Subjects:
breast cancer
cytotoxic effect
docosahexaenoic acid
eicosapentaenoic acid
omega-3 PUFA
phosphoinositide pathway
ERK pathway
in vitro studies
animal studies
human studies
Online Access:http://www.mdpi.com/2072-6643/9/3/185

Internet

http://www.mdpi.com/2072-6643/9/3/185

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