Dystroglycan Mediates Clustering of Essential GABAergic Components in Cerebellar Purkinje Cells

Dystroglycan Mediates Clustering of Essential GABAergic Components in Cerebellar Purkinje Cells

Muscle dystrophin–glycoprotein complex (DGC) links the intracellular cytoskeleton to the extracellular matrix. In neurons, dystroglycan and dystrophin, two major components of the DGC, localize in a subset of GABAergic synapses, where their function is unclear. Here we used mouse models to analyze t...

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Bibliographic Details
Main Authors: Federica Briatore, Giulia Pregno, Silvia Di Angelantonio, Elena Frola, Maria Egle De Stefano, Cyrille Vaillend, Marco Sassoè-Pognetto, Annarita Patrizi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
neuroligin 2
GABAA receptors
cell adhesion molecules
dystrophin
synapse organizer
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2020.00164/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2020.00164/full

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