15-oxoeicosatetraenoic acid mediates monocyte adhesion to endothelial cell

Abstract Background A great number of studies reported that 12/15-lipoxygenase (12/15-LO) played an important role in atherosclerosis. And its arachidonic acid(AA) metabolite, 15(S)-hydroperoxy-5,8,11,13-(Z,Z,Z,E)-eicosatetraenoic acid (15(S)-HETE), is demonstrated to mediate endothelial dysfunction...

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Bibliographic Details
Main Authors: Guohua Ma, Bing Pan, Sufen Ren, Caixia Guo, Yansong Guo, Lixin Wei, Lemin Zheng, Buxing Chen
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Lipids in Health and Disease
Subjects:
PKC
Online Access:http://link.springer.com/article/10.1186/s12944-017-0518-2