Serum markers glial fibrillary acidic protein and neurofilament light for prognosis and monitoring in cognitively normal older people: a prospective memory clinic-based cohort study

Summary: Background: Serum glial fibrillary acidic protein (GFAP) and neurofilament light (NfL) are putative non-amyloid blood-based biomarkers indicative of ongoing inflammatory and neurodegenerative disease processes. We aimed to assess their prognostic and monitoring value for progression to dem...

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Bibliographic Details
Main Authors: Inge M W Verberk, MSc, Malika B Laarhuis, MSc, Karlijn A van den Bosch, MSc, Jarith L Ebenau, MD, Mardou van Leeuwenstijn, Niels D Prins, MD, Philip Scheltens, ProfMD, Charlotte E Teunissen, ProfPhD, Wiesje M van der Flier, ProfPhD
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:The Lancet. Healthy Longevity
Online Access:http://www.sciencedirect.com/science/article/pii/S2666756820300611