The population genetics of dN/dS.
Evolutionary pressures on proteins are often quantified by the ratio of substitution rates at non-synonymous and synonymous sites. The dN/dS ratio was originally developed for application to distantly diverged sequences, the differences among which represent substitutions that have fixed along indep...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-12-01
|
| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2596312?pdf=render |