IL-10 Producing B Cells Ability to Induce Regulatory T Cells Is Maintained in Rheumatoid Arthritis

IL-10 Producing B Cells Ability to Induce Regulatory T Cells Is Maintained in Rheumatoid Arthritis

Despite growing evidence highlighting the relevance of increasing IL-10-producing B cells (B10+cells) in autoimmune diseases, their functions in patients are still unknown. The aim of this study was to evaluate the functions of CpG-induced B10+ cells isolated from healthy controls (HC) and rheumatoi...

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Bibliographic Details
Main Authors: Julie Mielle, Rachel Audo, Michael Hahne, Laurence Macia, Bernard Combe, Jacques Morel, Claire Daien
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
regulatory B cell
autoimmunity
interleukin 10
programmed death-ligand 2
rheumatoid arthritis
B10
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00961/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00961/full

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