Plasma Proteomic Profiling in Hereditary Breast Cancer Reveals a BRCA1-Specific Signature: Diagnostic and Functional Implications.

Breast cancer (BC) is a leading cause of death among women. Among the major risk factors, an important role is played by familial history of BC. Germ-line mutations in BRCA1/2 genes account for most of the hereditary breast and/or ovarian cancers. Gene expression profiling studies have disclosed spe...

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Main Authors: Domenica Scumaci, Laura Tammè, Claudia Vincenza Fiumara, Giusi Pappaianni, Antonio Concolino, Emanuela Leone, Maria Concetta Faniello, Barbara Quaresima, Enrico Ricevuto, Francesco Saverio Costanzo, Giovanni Cuda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4465499?pdf=render