Enhancement of peripheral nerve regrowth by the purine nucleoside analog and cell cycle inhibitor, roscovitine

Peripheral nerve regeneration is a slow process that can be associated with limited outcomes and thus, a search for novel and effective therapy for peripheral nerve injury and disease is crucial. Here, we found that roscovitine, a synthetic purine nucleoside analog, enhances neurite outgrowth in ne...

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Bibliographic Details
Main Authors: Vincent Law, Sophi Dong, Jesusa L. Rosales, Myung-Yung Jeong, Douglas Zochodne, Ki-Young Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00238/full