Immunogenic tumor cell death promotes dendritic cell migration and inhibits tumor growth via enhanced T cell immunity

Summary: Immunogenic tumor cell death enhances anti-tumor immunity. However, the mechanisms underlying this effect are incompletely understood. We established a system to induce tumor cell death in situ and investigated its effect on dendritic cell (DC) migration and T cell responses using intravita...

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Bibliographic Details
Main Authors: Taiki Moriya, Kurumi Kitagawa, Yuuki Hayakawa, Hiroaki Hemmi, Tsuneyasu Kaisho, Satoshi Ueha, Ryoyo Ikebuchi, Ippei Yasuda, Yasutaka Nakanishi, Tetsuya Honda, Koji Matsushima, Kenji Kabashima, Mizuki Ueda, Yutaka Kusumoto, Tatyana Chtanova, Michio Tomura
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221003928