Prostanoid receptor EP1 and Cox-2 in injured human nerves and a rat model of nerve injury: a time-course study

<p>Abstract</p> <p>Background</p> <p>Recent studies show that inflammatory processes may contribute to neuropathic pain. Cyclooxygenase-2 (Cox-2) is an inducible enzyme responsible for production of prostanoids, which may sensitise sensory neurones via the EP1 receptor....

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Main Authors: Collins Sue D, Day Nicola C, Chessell Iain P, Gray Roy A, Yiangou Yiangos, Casula Maria A, Facer Paul, Durrenberger Pascal F, Bingham Sharon, Wilson Alex W, Elliot David, Birch Rolfe, Anand Praveen
Format: Article
Language:English
Published: BMC 2006-01-01
Series:BMC Neurology
Online Access:http://www.biomedcentral.com/1471-2377/6/1