LAMR1 restricts Zika virus infection by attenuating the envelope protein ubiquitination

Zika virus (ZIKV) infection can cause severe neurological disorders, including Guillain–Barre syndrome and meningoencephalitis in adults and microcephaly in fetuses. Here, we reveal that laminin receptor 1 (LAMR1) is a novel host resistance factor against ZIKV infection. Mechanistically, we found th...

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Bibliographic Details
Main Authors: Dingwen Hu, Yingchong Wang, Aixin Li, Qin Li, Caifeng Wu, Muhammad Adnan Shereen, Shanyu Huang, Kailang Wu, Ying Zhu, Wenbiao Wang, Jianguo Wu
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Virulence
Subjects:
Online Access:http://dx.doi.org/10.1080/21505594.2021.1948261