Study of superoxide- and NO-dependent protective mechanisms of N-acetylcysteine and losartan in ratʼs aorta and liver under streptozoticin-induced type 1 diabetes mellitus

Study of superoxide- and NO-dependent protective mechanisms of N-acetylcysteine and losartan in ratʼs aorta and liver under streptozoticin-induced type 1 diabetes mellitus

Aim. The aim of the research was to investigate superoxide- (SR) and NO-dependent mechanisms of action of N-acetylcysteine (NAC) and losartan (LOS) in aorta and liver of rats with type 1 diabetes mellitus (DMI). Methods. Diabetic rats were treated with NAC (1.5g/kg), LOS (20mg/kg) or combination (N...

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Bibliographic Details
Main Authors: Inna Sytnyk, Anatoliy Burlaka, Anastasia Vovk, Mykola Khaitovych
Format: Article
Language:English
Published: PC Technology Center 2017-12-01
Series:ScienceRise: Pharmaceutical Science
Subjects:
стрептозотоцин
супероксид
аорта
печінка
щури
N-ацетилцистеїн
лозартан
Online Access:http://journals.uran.ua/sr_pharm/article/view/119490

Internet

http://journals.uran.ua/sr_pharm/article/view/119490

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