Immunomodulatory Effect of Pregnancy on Leukocyte Populations in Patients With Multiple Sclerosis: A Comparison of Peripheral Blood and Decidual Placental Tissue

Immunomodulatory Effect of Pregnancy on Leukocyte Populations in Patients With Multiple Sclerosis: A Comparison of Peripheral Blood and Decidual Placental Tissue

Pregnancy is a naturally occurring disease modifier of multiple sclerosis (MS) associated with a substantial reduction in relapse rate. To date, attempts to explain this phenomenon have focused on systemic maternal immune cell composition, with contradictory results. To address this matter, we compa...

Full description

Bibliographic Details
Main Authors: Michela Spadaro, Serena Martire, Luca Marozio, Daniela Mastromauro, Elena Montanari, Simona Perga, Francesca Montarolo, Federica Brescia, Alessia Balbo, Giovanni Botta, Chiara Benedetto, Antonio Bertolotto
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
multiple sclerosis
pregnancy
immunomodulation
peripheral blood
placenta
regulatory T cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01935/full

Similar Items

Similar Items