Immunomodulatory Effect of Pregnancy on Leukocyte Populations in Patients With Multiple Sclerosis: A Comparison of Peripheral Blood and Decidual Placental Tissue

Immunomodulatory Effect of Pregnancy on Leukocyte Populations in Patients With Multiple Sclerosis: A Comparison of Peripheral Blood and Decidual Placental Tissue

Pregnancy is a naturally occurring disease modifier of multiple sclerosis (MS) associated with a substantial reduction in relapse rate. To date, attempts to explain this phenomenon have focused on systemic maternal immune cell composition, with contradictory results. To address this matter, we compa...

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Bibliographic Details
Main Authors: Michela Spadaro, Serena Martire, Luca Marozio, Daniela Mastromauro, Elena Montanari, Simona Perga, Francesca Montarolo, Federica Brescia, Alessia Balbo, Giovanni Botta, Chiara Benedetto, Antonio Bertolotto
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
multiple sclerosis
pregnancy
immunomodulation
peripheral blood
placenta
regulatory T cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01935/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.01935/full

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