Increased glutamate synaptic transmission in the nucleus raphe magnus neurons from morphine-tolerant rats

<p>Abstract</p> <p>Currently, opioid-based drugs are the most effective pain relievers that are widely used in the treatment of pain. However, the analgesic efficacy of opioids is significantly limited by the development of tolerance after repeated opioid administration. Glutamate...

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Bibliographic Details
Main Authors: Pan Zhizhong Z, Bie Bihua
Format: Article
Language:English
Published: SAGE Publishing 2005-02-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/1/1/7