Study of molecular mechanisms of pro-apoptotic activity of NCX 4040, a novel nitric oxide-releasing aspirin, in colon cancer cell lines

<p>Abstract</p> <p>Background</p> <p>Despite numerous studies aimed at verifying the antitumor activity of nitric oxide-releasing nonsteroidal antiflammatory drugs (NO-NSAIDs), little is known about the molecular targets responsible for their antineoplastic properties....

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Bibliographic Details
Main Authors: Vannini Ivan, Medri Laura, Fabbri Francesco, Ulivi Paola, Rosetti Marco, Tesei Anna, Bolla Manlio, Amadori Dino, Zoli Wainer
Format: Article
Language:English
Published: BMC 2007-10-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/5/1/52