Epitope dampening monotypic measles virus hemagglutinin glycoprotein results in resistance to cocktail of monoclonal antibodies.

Epitope dampening monotypic measles virus hemagglutinin glycoprotein results in resistance to cocktail of monoclonal antibodies.

The measles virus (MV) is serologically monotypic. Life-long immunity is conferred by a single attack of measles or following vaccination with the MV vaccine. This is contrary to viruses such as influenza, which readily develop resistance to the immune system and recur. A better understanding of fac...

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Bibliographic Details
Main Authors: Patrycja J Lech, Gregory J Tobin, Ruth Bushnell, Emily Gutschenritter, Linh D Pham, Rebecca Nace, Els Verhoeyen, François-Loïc Cosset, Claude P Muller, Stephen J Russell, Peter L Nara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3536790?pdf=render

Internet

http://europepmc.org/articles/PMC3536790?pdf=render

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