Ionizing radiation, ion transports and radioresistance of cancer cells

Ionizing radiation, ion transports and radioresistance of cancer cells

The standard treatment of many tumor entities comprises fractionated radiation therapy which applies ionizing radiation to the tumor-bearing target volume. Ionizing radiation causes double-strand breaks in the DNA backbone that result in cell death if the number of DNA double-strand breaks exceeds t...

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Bibliographic Details
Main Authors: Stephan Michael Huber, Lena eButz, Benjamin eStegen, Dominik eKlumpp, Norbert eBraun, Peter eRuth, Franziska eEckert
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-08-01
Series:Frontiers in Physiology
Subjects:
DNA Repair
Ion Channels
cell migration
radiation therapy
Chromatin remodeling
cell cycle control
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00212/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00212/full

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