A novel conserved targeting motif found in ABCA transporters mediates trafficking to early post-Golgi compartments[S]

A novel conserved targeting motif found in ABCA transporters mediates trafficking to early post-Golgi compartments[S]

The ATP binding cassette, class A (ABCA) proteins are homologous polytopic transmembrane transporters that function as lipid pumps at distinct subcellular sites in a variety of cells. Located within the N terminus of these transporters, there exists a highly conserved xLxxKN motif of unknown functio...

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Bibliographic Details
Main Authors: Michael F. Beers, Arie Hawkins, Henry Shuman, Ming Zhao, Jennifer L. Newitt, Jean Ann Maguire, Wenge Ding, Surafel Mulugeta
Format: Article
Language:English
Published: Elsevier 2011-08-01
Series:Journal of Lipid Research
Subjects:
ATP binding cassette, class A
ABCA3
protein trafficking
post-Golgi sorting
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520369224

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520369224

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