TGF-β1/IL-11/MEK/ERK signaling mediates senescence-associated pulmonary fibrosis in a stress-induced premature senescence model of Bmi-1 deficiency

TGF-β1/IL-11/MEK/ERK signaling mediates senescence-associated pulmonary fibrosis in a stress-induced premature senescence model of Bmi-1 deficiency

Lung fibrosis: calling TIME on disease progression Targeting cellular signals that are increased in lung fibrosis may help halt disease progression. The build-up of scarred and thickened tissues in the lungs associated with aging and cellular deterioration is known as senescence-associated pulmonary...

Full description

Bibliographic Details
Main Authors: Haiyun Chen, Hongjie Chen, Jialong Liang, Xin Gu, Jiawen Zhou, Chunfeng Xie, Xianhui Lv, Rong Wang, Qing Li, Zhiyuan Mao, Haijian Sun, Guoping Zuo, Dengshun Miao, Jianliang Jin
Format: Article
Language:English
Published: Nature Publishing Group 2020-01-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-019-0371-7

Internet

https://doi.org/10.1038/s12276-019-0371-7

Similar Items