Solvent effects on the structure-property relationship of anticonvulsant hydantoin derivatives: A solvatochromic analysis
<p>Abstract</p> <p>Considering the pharmaceutical importance of hydantoins, a set of 25 derivatives of phenytoin, nirvanol and 5-methyl-5-phenylhydantoin, the lipophilicities of which were gradually increased by the introduction of different alkyl, cycloalkyl and alkenyl groups in...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-10-01
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Series: | Chemistry Central Journal |
Online Access: | http://journal.chemistrycentral.com/content/5/1/62 |