Solvent effects on the structure-property relationship of anticonvulsant hydantoin derivatives: A solvatochromic analysis

<p>Abstract</p> <p>Considering the pharmaceutical importance of hydantoins, a set of 25 derivatives of phenytoin, nirvanol and 5-methyl-5-phenylhydantoin, the lipophilicities of which were gradually increased by the introduction of different alkyl, cycloalkyl and alkenyl groups in...

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Bibliographic Details
Main Authors: Trišović Nemanja, Valentić Nataša, Ušćumlić Gordana
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Chemistry Central Journal
Online Access:http://journal.chemistrycentral.com/content/5/1/62