Protective and Pathogenic Roles of CD8+ T Lymphocytes in Murine Orientia tsutsugamushi Infection.

T cells are known to contribute to immune protection against scrub typhus, a potentially fatal infection caused by the obligate intracellular bacterium Orientia (O.) tsutsugamushi. However, the contribution of CD8+ T cells to protection and pathogenesis during O. tsutsugamushi infection is still unk...

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Bibliographic Details
Main Authors: Matthias Hauptmann, Julia Kolbaum, Stefanie Lilla, David Wozniak, Mohammad Gharaibeh, Bernhard Fleischer, Christian A Keller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5015871?pdf=render