Cell shape regulates subcellular organelle location to control early Ca2+ signal dynamics in vascular smooth muscle cells

Cell shape regulates subcellular organelle location to control early Ca2+ signal dynamics in vascular smooth muscle cells

Abstract The shape of the cell is connected to its function; however, we do not fully understand underlying mechanisms by which global shape regulates a cell’s functional capabilities. Using theory, experiments and simulation, we investigated how physiologically relevant cell shape changes affect su...

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Bibliographic Details
Main Authors: R. C. Calizo, M. K. Bell, A. Ron, M. Hu, S. Bhattacharya, N. J. Wong, W. G. M. Janssen, G. Perumal, P. Pederson, S. Scarlata, J. Hone, E. U. Azeloglu, P. Rangamani, R. Iyengar
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-74700-x

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https://doi.org/10.1038/s41598-020-74700-x

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