Single-cell transcriptomes and whole-brain projections of serotonin neurons in the mouse dorsal and median raphe nuclei

Single-cell transcriptomes and whole-brain projections of serotonin neurons in the mouse dorsal and median raphe nuclei

Serotonin neurons of the dorsal and median raphe nuclei (DR, MR) collectively innervate the entire forebrain and midbrain, modulating diverse physiology and behavior. To gain a fundamental understanding of their molecular heterogeneity, we used plate-based single-cell RNA-sequencing to generate a co...

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Bibliographic Details
Main Authors: Jing Ren, Alina Isakova, Drew Friedmann, Jiawei Zeng, Sophie M Grutzner, Albert Pun, Grace Q Zhao, Sai Saroja Kolluru, Ruiyu Wang, Rui Lin, Pengcheng Li, Anan Li, Jennifer L Raymond, Qingming Luo, Minmin Luo, Stephen R Quake, Liqun Luo
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-10-01
Series:eLife
Subjects:
serotonin
sc-RNAseq
dorsal raphe
medial raphe
intersectional labeling
single cell reconstruction
Online Access:https://elifesciences.org/articles/49424

Internet

https://elifesciences.org/articles/49424

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