Antitumor Activity of 2,9-Di-Sec-Butyl-1,10-Phenanthroline.

Antitumor Activity of 2,9-Di-Sec-Butyl-1,10-Phenanthroline.

The anti-tumor effect of a chelating phen-based ligand 2,9-di-sec-butyl-1,10-phenanthroline (dsBPT) and its combination with cisplatin were examined in both lung and head and neck cancer cell lines and xenograft animal models in this study. The effects of this agent on cell cycle and apoptosis were...

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Bibliographic Details
Main Authors: Dongsheng Wang, Shifang Peng, A R M Ruhul Amin, Mohammad Aminur Rahman, Sreenivas Nannapaneni, Yuan Liu, Dong M Shin, Nabil F Saba, Jack F Eichler, Zhuo G Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5199049?pdf=render

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http://europepmc.org/articles/PMC5199049?pdf=render

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