Sodium nitroprusside prevents the detrimental effects of glucose on the neurovascular unit and behaviour in zebrafish

Sodium nitroprusside prevents the detrimental effects of glucose on the neurovascular unit and behaviour in zebrafish

Diabetes is associated with dysfunction of the neurovascular unit, although the mechanisms of this are incompletely understood and currently no treatment exists to prevent these negative effects. We previously found that the nitric oxide (NO) donor sodium nitroprusside (SNP) prevents the detrimental...

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Bibliographic Details
Main Authors: Karishma Chhabria, Avgoustinos Vouros, Caroline Gray, Ryan B. MacDonald, Zhen Jiang, Robert Neil Wilkinson, Karen Plant, Eleni Vasilaki, Clare Howarth, Timothy J. A. Chico
Format: Article
Language:English
Published: The Company of Biologists 2019-09-01
Series:Disease Models & Mechanisms
Subjects:
Nitric oxide
NO donor
Hyperglycemia
Diabetes
Neurovascular coupling
Online Access:http://dmm.biologists.org/content/12/9/dmm039867

Internet

http://dmm.biologists.org/content/12/9/dmm039867

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