Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation

Abstract Targeting regulatory signaling pathways that control human bone marrow stromal (skeletal or mesenchymal) stem cell (hBMSC) differentiation and lineage fate determination is gaining momentum in the regenerative medicine field. Therefore, to identify the central regulatory mechanism of osteob...

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Bibliographic Details
Main Authors: Mona Elsafadi, Tasneem Shinwari, Sami Al-Malki, Muthurangan Manikandan, Amer Mahmood, Abdullah Aldahmash, Musaad Alfayez, Moustapha Kassem, Nehad M. Alajez
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-41543-0