Optimization of Conditions for the Synthesis and Oxidation of 5,8-Dimethoxy-2-methyl-3,4-dihydroisoquinolin-1(2H)-one into Novel 2-Methylisoquinoline-1,5,8(2H)-trione

Optimization of Conditions for the Synthesis and Oxidation of 5,8-Dimethoxy-2-methyl-3,4-dihydroisoquinolin-1(2H)-one into Novel 2-Methylisoquinoline-1,5,8(2H)-trione

<p>Due to stability issue of isoquinolone’s their <em>N</em>-methylation is a challenging task, achieved the synthesis of <em>N</em>-methylated 2-methylisoquinoline-1,5,8(2H)-trione using readily available precursor 2-(2,5-dimethoxyphenyl)ethanamine <em>via</em...

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Bibliographic Details
Main Authors: Basharat Ali, Faiz Ahmed, Nusrat Shafiq, Muhammad Nasrula
Format: Article
Language:English
Published: Universidade Federal de Mato Grosso do Sul 2020-05-01
Series:Orbital: The Electronic Journal of Chemistry
Subjects:
catalyst ratio
ceric ammonium nitrate
isoquinolone’s
n-methylation
oxidation
Online Access:http://orbital.ufms.br/index.php/Chemistry/article/view/1432

Internet

http://orbital.ufms.br/index.php/Chemistry/article/view/1432

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