PRC1 Prevents Replication Stress during Chondrogenic Transit Amplification
Transit amplification (TA), a state of combined, rapid proliferative expansion and differentiation of stem cell-descendants, remains poorly defined at the molecular level. The Polycomb Repressive Complex 1 (PRC1) protein BMI1 has been localized to TA compartments, yet its exact role in TA is unclear...
Main Authors: | , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-12-01
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Series: | Epigenomes |
Subjects: | |
Online Access: | https://www.mdpi.com/2075-4655/1/3/22 |