In vitro induction of regulatory CD4+CD8α+ T cells by TGF-β, IL-7 and IFN-γ.

In vitro CD4(+) T cell differentiation systems have made important contributions to understanding the mechanisms underlying the differentiation of naive CD4(+) T cells into effector cells with distinct biological functions. Mature CD4(+) T cells expressing CD8αα homodimers are primarily found in the...

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Bibliographic Details
Main Authors: Luc Van Kaer, Whitney A S Rabacal, Holly M Scott Algood, Vrajesh V Parekh, Danyvid Olivares-Villagómez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3701067?pdf=render