Bio-inspired iron-catalyzed oxidation of alkylarenes enables late-stage oxidation of complex methylarenes to arylaldehydes
Oxidation of toluenes to benzaldehydes is usually accompanied by overoxidation products. Here, the authors report an iron-catalysed aerobic oxidation of methylarenes to benzaldehydes with high yields and selectivities, even in presence of boronic acid groups and in complex natural products and drugs...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-06-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-10414-7 |