Epigenetic response of imprinted domains during carcinogenesis

Epigenetic response of imprinted domains during carcinogenesis

Abstract Background Imprinted domains have been identified as targets for aberrant DNA methylation during carcinogenesis, but it remains unclear when these epigenetic alterations occur and how they contribute to tumor progression. Epigenetic instability at key cis-regulatory elements within imprinte...

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Bibliographic Details
Main Authors: Corey L. Bretz, Ingeborg M. Langohr, Joomyeong Kim
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Clinical Epigenetics
Subjects:
DNA methylation
Genomic imprinting
Imprinting control regions
Imprinted genes
Cancer
Carcinogenesis
Online Access:http://link.springer.com/article/10.1186/s13148-017-0393-8

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http://link.springer.com/article/10.1186/s13148-017-0393-8

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