Monoclonal Antibody Recognizing a Core Epitope on Mucin

Monoclonal antibody TH1 (IgM) was prepared by immunizing mice with deglycosylated (TFMSA-treated) cystic fibrosis mucin. TH1 reacted strongly with TFMSA treated cystic fibrosis mucin but not with the fully glycosylated mucin, indicating reactivity with a core mucin epitope. TH1 showed no reactivity...

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Bibliographic Details
Main Authors: Peter L. Devine, Rachel J. Quin, Paul W. Shield, Yew Wah Liew, John K. Sheehan, David J. Thornton
Format: Article
Language:English
Published: Hindawi Limited 1998-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/1998/678434