Preconditioning of mesenchymal stromal cells with low-intensity ultrasound: influence on chondrogenesis and directed SOX9 signaling pathways
Abstract Background Continuous low-intensity ultrasound (cLIUS) facilitates the chondrogenic differentiation of human mesenchymal stromal cells (MSCs) in the absence of exogenously added transforming growth factor-beta (TGFβ) by upregulating the expression of transcription factor SOX9, a master regu...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-01-01
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Series: | Stem Cell Research & Therapy |
Online Access: | https://doi.org/10.1186/s13287-019-1532-2 |