Extreme clonality in lymphoblastoid cell lines with implications for allele specific expression analyses.
Lymphoblastoid cell lines (LCL) are being actively and extensively used to examine the expression of specific genes and genome-wide expression profiles, including allele specific expression assays. However, it has recently been shown that approximately 10% of human genes exhibit random patterns of m...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-08-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2494943?pdf=render |