Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin

<p>Abstract</p> <p>Survivin (<it>BIRC5</it>), a member of the inhibitor of apoptosis protein (IAP) family that inhibits caspases and blocks cell death is highly expressed in cancer and is associated with a poorer clinical outcome. Functioning simultaneously during cell...

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Bibliographic Details
Main Authors: Janik John E, Citrin Deborah, Lopez-Chavez Ariel, Kelly Ronan J, Morris John C
Format: Article
Language:English
Published: BMC 2011-04-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/10/1/35