From in silico to in vitro: a trip to reveal flavonoid binding on the Rattus norvegicus Kir6.1 ATP-sensitive inward rectifier potassium channel
Background ATP-sensitive inward rectifier potassium channels (Kir), are a potassium channel family involved in many physiological processes. KATP dysfunctions are observed in several diseases such as hypoglycaemia, hyperinsulinemia, Prinzmetal angina–like symptoms, cardiovascular diseases. Methods A...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2018-05-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/4680.pdf |