Hot melt granulation method for the preparation of floating matrix tablets of Tolperison Hydrochloride
Tolperisone HCl is a centrally muscles relaxant drug. It is a highly water-soluble drug. It has a biological half-life of 1.5–2.5 h. It has absorption window in the small intestine and unstable in intestinal pH 4 to 7. Gastroretentive drug delivery systems have shown to be of better significance in...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2018-12-01
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Series: | Future Journal of Pharmaceutical Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2314724517300535 |