Hot melt granulation method for the preparation of floating matrix tablets of Tolperison Hydrochloride

Tolperisone HCl is a centrally muscles relaxant drug. It is a highly water-soluble drug. It has a biological half-life of 1.5–2.5 h. It has absorption window in the small intestine and unstable in intestinal pH 4 to 7. Gastroretentive drug delivery systems have shown to be of better significance in...

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Bibliographic Details
Main Authors: Ankita U. Patel, Dipti V. Caudhari, Pranav J. Shah, Shailesh A. Shah
Format: Article
Language:English
Published: SpringerOpen 2018-12-01
Series:Future Journal of Pharmaceutical Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S2314724517300535