Association of <it>IREB2 </it>and <it>CHRNA3 </it>polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency

Association of <it>IREB2 </it>and <it>CHRNA3 </it>polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency

<p>Abstract</p> <p>Background</p> <p>The development of COPD in subjects with alpha-1 antitrypsin (AAT) deficiency is likely to be influenced by modifier genes. Genome-wide association studies and integrative genomics approaches in COPD have demonstrated significant ass...

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Bibliographic Details
Main Authors: Kim Woo Jin, Wood Alice M, Barker Alan F, Brantly Mark L, Campbell Edward J, Eden Edward, McElvaney Gerard, Rennard Stephen I, Sandhaus Robert A, Stocks James M, Stoller James K, Strange Charlie, Turino Gerard, Silverman Edwin K, Stockley Robert A, DeMeo Dawn L
Format: Article
Language:English
Published: BMC 2012-02-01
Series:Respiratory Research
Subjects:
<it>CHRNA3</it>
Chronic obstructive pulmonary disease
Genetic association analysis
Genetic modifiers
<it>IREB2</it>
Online Access:http://respiratory-research.com/content/13/1/16

Internet

http://respiratory-research.com/content/13/1/16

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