Assessment of the Role of NO-cGMP Pathway in Orthodontic Tooth Movement Using PDE5 Inhibitors: An Animal Study

Assessment of the Role of NO-cGMP Pathway in Orthodontic Tooth Movement Using PDE5 Inhibitors: An Animal Study

Objectives: Nitric oxide (NO) is a signaling molecule that mediates mechanical bone loading. Cyclic guanosine 3', 5' monophosphate (cGMP) is a NO-induced effector molecule. The aim of this study was to assess the effect of NO-cGMP pathway on orthodontic tooth movement (OTM) in rats by u...

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Main Authors: Amir Hossein Mirhashemi, Mohammad Sadegh Ahmad Akhoundi, Rezvaneh Ghazanfari, Shahroo Etemad-Moghadam, Mojgan Alaeddini, Azam Khorshidian, Ahmad Reza Dehpour, Nafiseh Momeni
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2017-01-01
Series:Frontiers in Dentistry
Subjects:
Nitric Oxide
Phosphodiesterase 5 Inhibitors
Tooth Movement Techniques
Online Access:https://jdt.tums.ac.ir/index.php/jdt/article/view/1536

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https://jdt.tums.ac.ir/index.php/jdt/article/view/1536

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