Stochastic cytokine expression induces mixed T helper cell States.

During eukaryotic development, the induction of a lineage-specific transcription factor typically drives differentiation of multipotent progenitor cells, while repressing that of alternative lineages. This process is often mediated by some extracellular signaling molecules, such as cytokines that ca...

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Bibliographic Details
Main Authors: Miaoqing Fang, Huangming Xie, Stephanie K Dougan, Hidde Ploegh, Alexander van Oudenaarden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-07-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3728019?pdf=render