Downregulation of CDKN2A and suppression of cyclin D1 gene expressions in malignant gliomas

<p>Abstract</p> <p>Background</p> <p>Malignant gliomas are the most common in central nervous system cancer. Genome-wide association study identifies that CDKN2A was a susceptibility loci for glioma. The CDKN2A/cyclin-dependent kinase 4, 6/Retinoblastoma protein (Rb) pa...

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Bibliographic Details
Main Authors: li Lei, Li Yawei, Lv Guohua, Liu Weidong, Wang Bing
Format: Article
Language:English
Published: BMC 2011-08-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/30/1/76