Preparation of controlled porosity osmotic pump tablets for salvianolic acid and optimization of the formulation using an artificial neural network method
In this paper controlled porosity osmotic pump tablets (CPOPT) for salvianolic acid (SA) were prepared and optimized with experimental design methods including an artificial neutral network (ANN) method. Three causal factors, i.e., drug, osmotic pressure promoting agent rate, PEG400 content in coati...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2011-06-01
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| Series: | Acta Pharmaceutica Sinica B |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383511000037 |